Friday, October 31, 2008

What Causes Parkinson's?

No matter what I read about Parkinson's I am still intrigued the most by the question of what causes this difficult disease? Why does it sometimes seem to run in families, but more often than not seem to just affect someone out of the blue?

I have read extensively about possible causes mostly because knowing the exact cause can only help with finding a way to stop the disease and/or cure it. My own personal belief is that there is often a genetic pre-disposition, but that there is also generally something environmental that triggers the cell death that occurs. Then again I am sure that there are cases with no genetic link at all and other cases where the disease developed solely based on genetics. I'd love to know how this continuum from genetics to environment works.

I know a lot about several of the genes that are implicated as links to Parkinson's, but so far there is no smoking gun genetically. I also know that pesticides and heavy metals are often sited as environmental causes. The latest potential cause is that the heavy metals that often exist in wine can lead to Parkinson's (as well as some cancers). Just a few years ago the biggest "healthy thing" to do was to have 1 glass of red wine a day to protect your heart. So it seems that wine might protect your heart, but hurt you in other ways.

I do not believe we know at this time whether or not most of the sources implicated truly cause disease or protect us against disease. I am hoping that in due time these things will become more apparent. For now I am planning to live my life well and enjoy every moment. I don't plan to be overly worried about pesticides, heavy metals in wine or my genetics.

How about you? Would you want to know if you had a PD gene? Are you avoiding all pesticides and other possible environment causes? Let me know.

19 comments:

Anonymous said...

My fifty-seven year old father has Parkinson's Disease. He was diagnosed with early-onset Parkinson's Disease almost six years ago now (he was fifty-one then, but his doctors think he may have already been in the early stages of the disease during his mid-to-late thirties). At the time he was diagnosed, I was about to graduate from high school, completely naive & oblivious to what Parkinson's Disease even was. I can honestly say I was wholly unaware of the seriousness of the disease or the future struggles he and my family would face in the coming years as a result of his diagnosis.

But as my dad's Parkinson's disease has quickly progressed over the past six years, I have come to know the disease inside and out. That being said, I do believe there is a link between environmental factors, such as pesticides, to the development of Parkinson's Disease. My dad himself thinks that his Parkinson's may have developed as a result of working on farms as a summer job back when he was a teenager. Part of his job was spraying pesticides on crops, which therefore directly exposed him to their possible harmful effects.

I also believe there to be genetic predisposals in some individuals to Parkinson's Disease (myself included in this group). And when such genetic predisposals are combined with harmful environmental factors linked to Parkinson's Disease, I think the combination increases the odds of an individual developing the disease. However, this is my own personal opinon as I am clearly not a doctor, scientist, or expert on the subject. I am just a girl with a dad who has Parkinson's Disease, trying to put the puzzle pieces of this mysterious & relentless disease together.

Sometimes I wish there was an available genetic test I could take to determine if I myself might have Parkinson's Disease someday. Then I would know the truth & never have the question in the back of my mind. But on the other hand, what good would come from knowing this at the age of twenty-four, when no cure for Parkinson's Disease has been found yet?? As a young, active, & adventurous young lady, receiving bad news from such a test might just crush my spirit at this point in my life & keep me from enjoying and living in the moment.

After all, I have come to know that in life, anything can happen at any moment. None of us are even promised tomorrow. So why waste time worrying about tomorrow when today is all any of us truly have??? :)

~Meg B~

Unknown said...

I am one of three nurses that worked on the same floor. Pediatrics , I was the newest nurse to the unit. They both became disabled do to parkinsons. they were 4 and 10 years older than me. I am now in my 11th year of parkinsons. i have just filed for disability. No one seems interested in our connection!I am now a 52 yr. old female.

Martin, Jones, & Piemonte - Attorneys at Law said...

Viet Nam veterans with Parkinson's disease may now be entitled to service connected benefits. www.gpdisabilitylaw.com

David Chedester said...

I am a 28 year old that was diagnosed with Parkinson's Disease over a year ago, and my father also has the disease as well. He was diagnosed with PD when he was 51, and his grandfather also had the disease as well. Even with these extreme genetic connections, our neurologists are still hesitant to assume that we were born with the genetic disposition of having the disease. We just needed something the trigger the loss of dopamine cells. I was a college baseball player, and had a baseball lined off my right temple when I was 18. Coincidentally, my tremors showed up on the right side of my body, FIRST. After trips to see many neurologists and parkinson's specialists, none of them have been able to make a direct link to either genetics or environmental factors. While they all agree both have played some part in me developing the disease, there is no 100$ answer. I enjoy reading your positive outlook and blogs. I have taken a very similar approach and started my own blog to help cope with my disease. My blog is http://shakin-not-stirred.blogspot.com

Please continue posting, because it's people like you that we as a Parkinson's community need to help us become more positive and educate others!

Ausin Ortiz said...

(MUST READ: HOW I GOT CURED FROM PARKINSON'S DISEASE)
I am Austin, I was diagnosed of Parkinson's disease in November 2014. I was given medications like levodopa to slow down the progress of the disease. I suffered from this disease till my wife's co worker told my wife about a herbal doctor from Johannesburg, South Africa, who sells herbal medicines to cure all kinds of diseases including Parkinson's disease. We contacted this herbal doctor via his email and bought the Parkinson's disease herbal medicine from him. He sent it to me through courier service and i received it within 6 days. i applied it as instructed and was totally cured of the disease within 20-22 days of usage, all thanks to Dr Ejiro Mapipa. Contact him via his email, mapipaherbalclinic@gmail.com or call his mobile number on +27617403481 Goodluck

Jessica Bells Micheals said...

Here is the herbal Dr who can cure PD ( Parkinson Disease ) and other deadly diseases with the use of natural herbs. He is DR OSOJO the Super herbal doctor, he cured my 2 years Parkinson Virus and he can also cure yours as well, if you are having the same virus And other deadly diseases.
Here are his contact email address:( dr.osojoherbalcureofalldisease@gmail.com and dr.osojoherbalcureofalldisease@hotmail.com )
THERE ARE THE THINGS Dr. OSOJO CAN DO,
HERPES VIRUS CURE ,
HEPATITIS A,B,C, CURE,
HIV/AIDS CURE ,
CANCER CURE,
PREGNANCY PROBLEMS/INFERTILITY CURE,
LOU GEHRIG DISEASE/ AMYOTROPHIC LATERAL SCLEROSIS (ALS) CURE ETC.........
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Thank you Dr Osojo for saving me from PD

Unknown said...

My name Kamren Hamrick from Atlanta, Georgia,United States ...Parkinson disease has been ongoing in my family for long..I lost both parents to Parkinson and it is so much pain have not been able to get over. As we all know medically,there is no solution or cure for Parkinson disease and the cost for Medication is very expensive..Someone introduced me to a herbal doctor(Native Medical Practitioner)in GA..I showed the man all my Tests and Results and i told him i have already diagnosed with Parkinson disease and i have spent thousands of dollars on medication..I said i will like to try him cos someone introduced me to him..He asked me sorts of questions and i answered him correctly..To cut the story short,He gave me some medicinal herbs and he instructed me on how to apply theml..At first i was skeptical but i just gave it a try..I was on his Medication for 2 weeks and i used the herbs according to his prescription..i decided to visit my doctor for another test..Honestly speaking, i never believe all he was saying until after the test when my doctor mention the statement that am Parkinson disease negative and my doctor was shocked as well....If you are out there suffering from this deadly disease you can also contact him via email: drlusandaherbal@gmail.com or website on www.drlusandaherbal.weebly.com thanks

Unknown said...

I decided to share this to help someone out there who is still held with Parkinson's.
My dad suffered from parkinson's for 18 years and we traveled round the world from one hospital to another neurologist and spent thousands of dollars and even got scammed in this process of seeking a cure and the problem still persisted. He acted weird and aggressive and this was so scary. All thanks to Dr Lusanda who was able to use his herbal medicine to cure him permanently. He is one of the Honest men out there. If you want to contact him on how to get this herbal medicine or for info just reach him directly on drlusandaherbal@gmail.com or website on www.drlusandaherbals.weebly.com Thanks admin.

Barbara Macelli said...

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Unknown said...

My husband was misdiagnosed with PD in 2000. Very rapid deterioration and many queries eventually led to MSA (Multiple System Atrophy) diagnosis. A horrible, horrible condition robbing people of independence, dignity, movement, speech, continence, ability to swallow and breathe.we didn't know what to do we tried everything possible medically, we were waiting for his death then one day our daughter got back from work with the email of a herbal Dr saying her friend from work told her about a testimony on how Lusanda cured her mom from PD and it truely worked, we were desperate and sceptical but my daughter told me we got nothing to loose and i decided to give it a try. 4 weeks after he started taking the herb he regained his speech and today my husband is fully rocovered from this deadly disease called PD, this isn't a BS it is real you can also contact dr Lusanda on drlusandaherbal@gmail.com or website on www.drlusandaherbals.com

Unknown said...

HOW I GOT CURED FROM MULTIPLE SYSTEM ATROPHY DISEASE..
My name is Robert Williams, I thought i should share this here as someone may need this information; I was diagnosed of Multiple system Atrophy in February 2013, my doctor told me it has no permanent cure, i was given some medications to ease the situation, this continued till a friend of mine told me about Dr Odi from Africa who cured her father of Multiple System Atrophy disease and Glaucoma. I contacted this herbal doctor and bought the herbal medicine from him, i received it within 6 days and applied it as prescribed and was totally cured within 19 days of usage. my life is back again! Contact this herbal doctor via his email oyeyetemple@gmail.com or call +2348115531558

Jessica said...

TESTIMONY OF HOW I GOT CURED FROM HERPES SIMPLEX VIRUS
This is real take it serious, who will believe that a herb can cure herpes, i never believe that this will work, i have spend a lot getting drugs from the hospital to keep me healthy, it got to a time that i was waiting for is death to come because i was broke, one day i hard about this great man called DR.EHIZUELE who is well know for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and sent it through Online Courier Service for delivery, he gave my details to the Courier Office. they told me that 3-5 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the one week, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, i thought it was a joke, i went to other hospital and was also negative, thank you for saving my life, I promise I will always testify of your good works. if you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.ehizuelespelltemple@gmail.com
THESE ARE THE THINGS DR.EHIZUELE CAN DO
. HERPES
. HIV/AIDS
. CANCER

Unknown said...

ust got diagnosed with HSV1, and reading this actually made me feel like crawling and crying like a baby. The outbreak I have right now is genital and in my throat and mouth, I talked to the doctor who did the blood test on me and said over time that it would eventually get much better. She said that what I’m having is a massive outbreak and is unusual, but that it may be due to the fact that I stressed myself out over it so much. She also told me even though I have it in the genital area that It doesn't mean that I needed “private to private” contact to acquire it. But this did make me feel a whole lot better about the whole situation. For anyone else to have HSV1 after all this stress and pains am passing and the doctor saying all such of crap i was not convince by his Theory so i decided to go on the internet and saw this comments by Rose who testify about how she get cured by root and herbs by Dr AZUKA, when i first bump into it i didn't believe the comments at first so i decided to confront her on Facebook and really know what and how did it work because my doctor told me there is no cure for herpes, so i really contacted DR AZUKA, he responded in A minute the only thing he ever ask for was just the items of which he will use to prepare for the herbs, after all this he send the herbs through courier Services, within a week i was cure just like that without no struggle or stress, if you are out there in need of cure contact him with his email address: Dr.azukasolutionhome@gmail.com OR reach him on his mobile phone +2348132777335

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Lisa Nayna Tumelo said...

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4. ALS (Lou Gehrig’s disease)
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7. Emphysema
8. COPD (Chronic Obstructive Pulmonary Disease)
9. Asthma
10.Acute angle-closure Glaucoma
11. Diabetes
12.CHRONIC PANCREATIC
13.CHLAMYDIA
14.ZIKA VIRUS

joy bella said...

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isabella said...


My husband was diagnosed with early onset Parkinson's disease at 57.his symptoms were shuffling of feet,slurred speech, low volume speech, degradation of hand writing, horrible driving skills, right arm held at 45 degree angle, things were tough for me, but now he finally free from the disease with the help of total cure ultimate health home, he now walks properly and all symptoms has reversed, he had trouble with balance especially at night, getting into the shower and exiting it is difficult,getting into bed is also another thing he finds impossible.we had to find a better solution for his condition which has really helped him a lot,the biggest helped we had was ultimatehealthhome they walked us through the proper steps,am highly recommended this ultimatehealthhome@gmail.com to anyone who needs help.

Karen Houston said...

After was running around from doctor to doctor before we finally get rid of her PD ,at age 74 my mother noticed that her handwriting was getting smaller and I was writing faster as well. She also noticed a small tremor in her left hand. The doctor went over her different symptoms and he suspected she either had a small stroke or the beginnings of Parkinson 's disease. After finding a neurologist and some testing she was diagnosed with the beginning stages of Parkinson’s disease. That was 3 years ago. She take Sinimet four times a day to control the symptoms, which include falling, imbalance, gait problems, swallowing difficulties, and slurring of speech,This year, our family doctor started her on multivitamincare. org PD Herbal mixture, 15 weeks into treatment she improved dramatically. At the end of the full treatment course, the disease is totally under control. No case of dementia, hallucination, weakness, muscle pain or tremors.

matina said...


i was diagnosed of parkinson disease 5 years ago,i started azilect,then mirapex as the disease progressed in february last year,and i started on parkinson disease herbal medicine from ultimate life clinic,few months into the treatment i made a significant recovery,almost all my symptoms are gone,great improvement with my movement and balance,it been a year and life has been so good for me,reach them through there website at www.ultimatelifeclinic.com
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